Presentations from Top Biopharma in 2025
AbbVie Inc.
Analytical Ultracentrifugation Is a New Dynamic Platform Technology for Targeted Protein Degradation
Judith Ronau, PhD, Senior Scientist, AbbVie Inc.
Overview of the History and Progress of Botulinum Neurotoxins Therapy
Sathya Venkataramani, PhD, Director, Protein Science, AbbVie, Inc.
Amgen, Inc.
What Does It Take for a Successful Impurity Isolation—Exploring the Tools, Tactics, and Techniques
Kevin Crossley, Scientist, Synthetic Group, Amgen, Inc.
Strategies for High-Throughput Purification of Complex Multispecifics
Jeremy King, PhD, Senior Principal Scientist, Amgen, Inc.
Better, Faster, Stronger, Smarter: Transforming Drug Discovery with Cutting-Edge Automation
Daniel Yoo, Senior Principal Scientist, Large Molecule Discovery & Research Data Science, Amgen, Inc.
AstraZeneca
Engineering Solutions for Homogeneous Production of Asymmetric Bispecific Antibodies with the DuetMab Platform
John D. Bagert, PhD, Associate Director, Biologics Engineering, AstraZeneca
Production of Native Recombinant Proteins Using a Novel Split Intein Affinity Technology
Robert I. Clifford, Scientist, AstraZeneca
Advancing HT Functional Assays for the Profiling of Multispecific Antibodies
Bushra Husain, PhD, Director of Assay, Profiling and Pharmacology, AstraZeneca
High-Throughput Developability Strategies to Support the Modern Pipeline and ML Models
Gilad Kaplan, PhD, Director, Biologics Engineering, AstraZeneca
Exploring a Deep Screening Platform & High-Throughput Processes to Improve AI Capabilities
Christopher Wassif, PhD, Director, Molecular Engineering & Antibody Technologies, AstraZeneca
High-Throughput Intact Mass QC: Aiming to Match High-Throughput Protein Production through Automated Data Processing with ProteinMetrics Byosphere
Xinbi Li, PhD, Associate Principal Scientist, Biologics Engineering, AstraZeneca
Biogen
Simultaneous Optimization of Antibody Specificity, Potency, and Pharmacokinetics through Charge Engineering
Mark C. Julian, PhD, Principal Scientist, Biologics Drug Discovery, Biogen
Boehringer Ingelheim Pharmaceuticals, Inc.
It’s Going to Take a Village: Standardizing Analytics for Better Machine Learning
Michael S. Marlow, PhD, Director, Biologics CMC Research, Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceuticals, Inc.
Implementing High-Throughput Developability Analytics to Drive Biotherapeutic Engineering
Andrew K. Urick, PhD, Principal Scientist, Protein Engineering, Boehringer-Ingelheim, Inc.
Bristol Myers Squibb Co.
Accelerating High-Throughput Production through Functional Assessments of Bispecifics
Kristoff Homan, PhD, Senior Principal Scientist, Discovery Biotherapeutics, Bristol Myers Squibb Co.
High-Throughput and Automation in Characterizing Novel Modalities and Beyond
Ben Niu, PhD, Principal Scientist, Discovery Biotherapeutics, Bristol Myers Squibb Co.
Eli Lilly and Company
Creation of a Versatile Automated Two-Step Purification System with Increased Throughput Capacity for Preclinical mAb Material Generation
Anthony S. Ransdell, Senior Principal Scientist, Biotechnology Discovery Research, Eli Lilly and Company
Genentech Inc.
Development and Qualification of Analytical Methods to Support Low-Concentration Drug Product in-Use Studies
Adithi Bhargava, Scientist, Late-Stage Pharmaceutical Development, Genentech Inc.
Dual Antibody Inhibition of KLK5 and KLK7 for Netherton Syndrome and Atopic Dermatitis
Cecilia Chiu, PhD, Scientist IV, Genentech Inc.
The Development of a High-Throughput Small-Scale Intracellular Expression Testing Platform for Non-Antibody Proteins
Christine L. Kugel, Principal Scientific Researcher, Biomolecular Resources, Genentech Inc.
Developing High-Throughput Small-Scale Secreted Protein Expression Screening Platform
Sairupa Paduchuri, Scientist III, Biomolecular Research, Genentech Inc.
High-Concentration Developability Approaches and Considerations
Jonathan Zarzar, Senior Principal Scientist and Group Leader, Pharmaceutical Development, Genentech Inc.
Accelerating Recombinant Adeno-Associated Virus (AAV) Production in Chinese Hamster Ovary (CHO) Cells
Thu Cao, PhD, Postdoctoral Fellow, R&D, Genentech Inc.
Gilead Sciences Inc.
High-Throughput Screening of Therapeutic Antibody Viscosity Using a Protein Large Language-Based Machine Learning Approach
Krishna D Bharadwaj Anapindi, Research Scientist, Biology, Gilead Sciences Inc.
Janssen Pharmaceuticals
Unravelling the Mechanism of Aggregation in Next-Gen Multispecific Antibodies
Michael Poltash, PhD, Principal Scientist, Cell Engineering and Analytical Sciences, Janssen Pharmaceuticals
Johnson & Johnson Innovative Medicine
Automation in Biologics Production & Characterization: Then, Now, and Future
Iman Farasat, PhD, Director, High Throughput Expression, ohnson & Johnson Innovative Medicine
Innovations in the Purification, antigen expression and labeling of HIV-1 Gag Viral-Like Particles (VLPs) for Native Membrane Protein Display
Neha Bhat, PhD, Sr Scientist, Biologics Discovery, Johnson & Johnson Innovative Medicine
End-to-End Automated Cell Culture Seed Production Platform
Daniel Poole, PhD, Senior Scientist, Biologics HTP Expression Sciences, Johnson & Johnson Innovative Medicine
Computational and ML Approaches for Targeted Protein Degradation
Nadeem A. Vellore, PhD, Principal Scientist, Johnson & Johnson Innovative Medicine
Kite Pharma
Critical Tools and Practices to Promote Data Integrity in a Protein Production Core
Christa Cortesio, PhD, Director, Protein Science, Protein Biochemistry & Analytics Core, Kite Pharma, a Gilead Company
Automated, High-Throughput Manufacturing and Screening of CAR T Cells
Sean Yoder, Research Automation Core Lead & Senior Manager, Cell Biology Research, Kite, a Gilead Company
Merck & Co. , Inc.
Coupling HT Expression with Automated Gene-to-Structure Data Acquisition and Analysis to Accelerate the Design-Make-Test-Analyze (DMTA) Cycle
James Kostas, Senior Scientist, Protein and Structural Chemistry, Merck & Co., Inc.
Employing Multiple Lenses to Characterize ADC in vitro/in vivo through Integrated Platforms
Jianzhong Wen, PhD, Principal Scientist, Group Leader, Merck & Co., Inc.
Novo Nordisk AS
Pfizer Inc.
Recombinant Protein Tools—Supporting Small Molecule Lead Discovery and Optimization Efforts
Oleg Brodsky, Senior Principal Scientist, Structural Biology & Protein Sciences, Pfizer Inc.
High-Throughput Membrane Protein Production Supporting Drug Discovery
Timothy K. Craig, PhD, Lab Head Protein Sciences, Pfizer Inc.
Sanofi
Purification Strategy Development Based on a Comprehensive HTP Screening Tool for Multispecific Molecules
Jane (Yongjing) Guo, PhD, Senior Principal Scientist & Lab Head, Large Molecules Research, Sanofi
Nano-DSF Technology as a Preliminary Decision-Making Tool for Long Term Stability Evaluation of Vaccine Formulations
Rahul Misra, PhD, Scientist, Biophysics and Process Analytical Technology, Sanofi
Manufacturability Assessments for Therapeutic Antibodies Reveal Liabilities Unique to Immunoglobulin Subclass
Charles G. Starr, PhD, Senior Scientist, Developability and Preformulation Sciences, Sanofi
As of October 18, 2024. Please see individual agenda pages for most up-to-date agenda.